Guanidine hydrochloride

Guanidine hydrochloride

Guanidine Monohydrochloride; 1-Hydroxy-1,2,3,4-tetrahydropyrimidine hydrochloride; 2-Amino-2-iminoethanamine hydrochloride; Aminoformamidine hydrochloride

CAS 50-01-1

Chemical Formula C₃H₇ClN₄

Molecular Weight 112.57 g/mol

Guanidine hydrochloride is a potent protein denaturant extensively utilized in the purification of proteins and nucleic acids. Widely recognized for its versatility, it plays a pivotal role in total RNA extraction experiments, dissolving proteins and disrupting cell structures while inactivating RNA enzymes.

Industrial Uses

1. Agrochemicals

  • Pesticide and Herbicide Synthesis: Guanidine hydrochloride is used in the agrochemical industry as an intermediate in synthesizing certain pesticides and herbicides. Guanidine derivatives exhibit bioactive properties that are useful for controlling pests and unwanted plants.
  • Fertilizer Production: Although less common, guanidine hydrochloride and its derivatives can sometimes be used in specialty fertilizers, enhancing nutrient uptake in crops.

2. Pharmaceuticals

  • Stabilizing Agent: In the pharmaceutical industry, Guanidine hydrochloride is used as a stabilizing agent for drugs and proteins, preventing aggregation and maintaining solubility. It helps to maintain the efficacy of protein-based drugs.
  • Intermediate in Drug Synthesis: It serves as a chemical intermediate in the synthesis of various pharmaceuticals, especially those targeting parasitic diseases like malaria, due to its ability to disrupt cellular membranes.

3. Chemical Synthesis

  • Resin Production: Guanidine hydrochloride is used as a hardening agent for urea-formaldehyde resins, which are utilized in producing adhesives, particleboards, and laminates. It enhances the curing process, leading to stronger and more durable end products.
  • Surface Treatment: It is used in surface treatment applications, such as in the preparation of metal and plastic surfaces before coating or painting, by modifying surface properties and improving adhesion.

4. Personal Care

  • Hair Care Products: In hair care formulations, Guanidine hydrochloride is sometimes used as a pH adjuster and to maintain the stability of hair relaxers. It helps in breaking down hair keratin to relax curly or frizzy hair.
  • Skin Care Products: It can act as a buffering agent in skincare products, aiding in maintaining the desired pH and enhancing the effectiveness and stability of other ingredients.

5. Polymers & Resins

  • Descaling Agent: In industrial cleaning processes, guanidine hydrochloride can act as a descaling agent to remove lime and other mineral deposits from equipment, especially in settings where biological materials are processed.
  • Production of Resins and Plastics: It is a key ingredient in synthesizing certain types of resins and plastics due to its reactive guanidine group, which can contribute to crosslinking and stabilization.

Specifications

Assay Typically ≥ 99%
Appearance White crystalline powder
Odor odorless
Boiling Point decomposes before boiling
Melting Point 164°C (327°F)
Density 1.35 g/cm³
Solubility Highly soluble in water
Viscosity 25°C
Flash Point 34.2℃

Hazard Symbols

Corrosives
Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of Guanidine hydrochloride in India?
The price of Guanidine hydrochloride can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91.979 979 2121 directly for a customized quote tailored to your needs.

2. Where can I buy Guanidine hydrochloride in India?
You can purchase Guanidine hydrochloride from MULTICHEM, a leading importer with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across India. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for Guanidine hydrochloride?
Our minimum order quantity (MOQ) for Guanidine hydrochloride is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of Guanidine hydrochloride supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.